Clinical perspective, offered as context rather than as advice.
Physical therapist weighing in on lean mass. I work with bariatric and metabolic patients daily.
The resistance training evidence is critical here:
The Lundgren 2024 JAMA paper[1] showed that structured resistance training preserved 73% more lean mass in GLP-1 patients vs medication alone. When discussing lean mass, we MUST include the exercise component.
My minimum prescription: 3x/week compound movements (squat, deadlift, press, row), progressive overload, 7-10K steps/day, and 1.2-1.6g protein/kg/day.
[1] Lundgren JR, et al. JAMA. 2024;331(1):38-48.
anders_CPH said:Sharing my comprehensive lab data relevant to lean mass: Biomarker Baseline Month 3 Month 6 Month 9 Weight (lbs) 255 250 225 215 A1C (%) 6.5 6.5 6.0…
This is exactly what I could not find anywhere else. Adding it to my notes with a link back to this thread.
Clinical perspective, offered as context rather than as advice.
DEXA scan update relevant to lean mass:
Scanned at months 0, 6, and 12. Here are the body comp numbers:
| Baseline | Month 6 | Month 12 | |
|---|---|---|---|
| Total mass | 253 lbs | 218 lbs | 220 lbs |
| Fat mass | 123 lbs | 73 lbs | 55 lbs |
| Lean mass | 161 lbs | 148 lbs | 157 lbs |
| Body fat % | 38% | 34% | 24% |
Lean mass preserved — actually GAINED 1-2 lbs thanks to progressive overload + 1.5g/kg protein. The lean mass discussion needs to include body comp data, not just scale weight.
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Shop Reference StandardsDr.RaviCardio said:DEXA scan update relevant to lean mass: Scanned at months 0, 6, and 12.
Mine went the same way, slower.
Moderator note: the sourcing question belongs in the vendor section and has been split out. Thread quality here is what the rules are for. Keep it up.