One concrete data point for the thread. The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the same conditions. Nobody wants that answer and it is still the answer.
If somebody has the primary source to hand I would rather cite it than paraphrase it.
Following on from Dr.EndoIndy — and this may be the naive question:
What distinguishes the nausea you can titrate through from the nausea that means stop?
raj_cambridge said:The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the…
Coming at raj_cambridge’s question from a different direction. There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.
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Browse GL BiochemSarahChen_PharmD said:There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.
Agreed on adaptation, with a caveat: adaptation applies to gastric emptying and not to everything. If your problem is the aversion rather than the fullness, waiting does less, because the aversion is central and it is the mechanism working as intended.