Dr.ReproEndo said:Vendor quality matters when discussing certificates of analysis.
This matches mine closely enough to be worth saying so out loud.
FDA_TrackerJim said:I tested my certificates of analysis batch through Janoshik — 98.4% purity.
Second this. Nothing to add that would improve it.
FDA_TrackerJim said:I tested my certificates of analysis batch through Janoshik — 98.4% purity.
COA red flags for certificates of analysis — here's what to look for when reviewing a Certificate of Analysis:
- No HPLC data: If there's no chromatography graph, it's not a real COA
- Exact 100% purity: Suspicious — real testing always shows slight variation
- No batch number: Can't trace back to specific production
- No endotoxin testing: For injectables, this is essential
- Template looks like it was made in Word: Professional labs have standardized formats
I have seen fake COAs that are literally photoshopped. Always verify independently if possible.
Sigma-Aldrich — Research-Grade Standards
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Shop Reference StandardsFDA_TrackerJim said:I tested my certificates of analysis batch through Janoshik — 98.4% purity.
HPLC results interpretation for certificates of analysis: when you get your Janoshik report back, here's what the numbers mean:
- Purity %: Should be >97%. Below 95% is concerning.
- Retention time: Should match reference standard for the peptide
- Related substances: Degradation products should be <2% total
- Single impurity: No individual impurity should exceed 1%
My last batch: 99.6% purity, 0.2% total related substances. Clean chromatogram with single sharp peak at expected retention time. Exactly what you want to see.
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