traveltech_sara said:Muscle fiber type changes during GLP-1-mediated weight loss, relevant to lean mass: preliminary biopsy data suggests that weight loss shifts the…
DEXA scan update relevant to lean mass:
Scanned at months 0, 6, and 12. Here are the body comp numbers:
| Baseline | Month 6 | Month 12 | |
|---|---|---|---|
| Total mass | 263 lbs | 218 lbs | 220 lbs |
| Fat mass | 123 lbs | 83 lbs | 55 lbs |
| Lean mass | 161 lbs | 154 lbs | 157 lbs |
| Body fat % | 40% | 34% | 24% |
Lean mass preserved — actually GAINED 1-2 lbs thanks to progressive overload + 1.5g/kg protein. The lean mass discussion needs to include body comp data, not just scale weight.
traveltech_sara said:Muscle fiber type changes during GLP-1-mediated weight loss, relevant to lean mass: preliminary biopsy data suggests that weight loss shifts the…
Back pain as a lean mass side effect: not from the medication itself, but from rapid body composition changes. Losing 45 lbs shifts your center of gravity and your core muscles need time to adjust.
Physical therapy has been essential. Core strengthening exercises (planks, dead bugs, bird dogs) daily for 10 minutes have eliminated my lower back pain. Your body is literally relearning how to carry itself.
Following on from traveltech_sara — and this may be the naive question:
Was that from a primary source or from a summary of one?
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View ResultsDr.PeteFamMed said:Back pain as a lean mass side effect: not from the medication itself, but from rapid body composition changes.
Filing a mild objection. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit. This treats a plausible mechanism as a demonstrated one. Plausible is where you start looking, not where you stop.
Dr.PeteFamMed said:Back pain as a lean mass side effect: not from the medication itself, but from rapid body composition changes.
Right, and the exception is worth naming rather than left implied, because the exception is where people get into trouble.