lisa_labSD said:The distinction that matters is unopened versus in use.
Agreed, though "tolerable" needs defining. A dose you tolerate by eating almost nothing is not tolerated, it is being paid for somewhere else — usually in lean mass, sometimes in adherence three months later.
JakeSmashed95 said:The dose-response is real but shallow at the top.
This answered a question I did not know how to ask. Printing the relevant bit and taking it with me.
lisa_labSD said:The distinction that matters is unopened versus in use.
I read this differently from lisa_labSD, on substance rather than tone. The trial means are being read too generously in this thread. STEP populations were selected, supported, and titrated by protocol, and the real-world curves are consistently a few points worse. That difference is not noise, it is what happens when you remove the study infrastructure.
Correct me if the detail matters more than I have assumed.
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Shop Reference StandardsThe figures, for anyone assembling their own picture. Practical: unopened, refrigerated at 2 to 8°C; in use, refrigerated and used within the preservative-limited window; never frozen; and a visual check every time — a haze that does not settle is a reason to stop, not to wonder.