wendy_avl said:If you are going to change something, change one thing and give it long enough to express itself.
Agreed on the substance. I would put less weight on the timescale, because two months of anything is not enough to distinguish a trend from a wobble.
wendy_avl said:If you are going to change something, change one thing and give it long enough to express itself.
Thank you for spelling out the reasoning rather than just the conclusion.
Adding the clinical framing, because it changes how the question reads. The mechanism and the magnitude are separate questions. Agreeing that something happens says nothing about whether it happens enough to act on.
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Browse GL BiochemOld thread, but it comes up first when you search for this, so it is worth updating. One habit that pays for itself: post the method alongside the number. A figure without its method cannot be checked, and an unchecked figure is how this community accumulates folklore.
Happy to go further on any of that.
hans_munich said:The mechanism and the magnitude are separate questions.
Adding the part of the answer the thread has not reached. Most of what circulates confidently in this community traces back to one summary of one study, and the qualifier was dropped somewhere in the third retelling.