PharmacoVig_BOS said:The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the…
That holds where the measurement is reliable. Where it is noisy — and a lot of what gets tracked here is noisy — the same reasoning produces confident nonsense.
PharmacoVig_BOS said:The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the…
Saving this. It is the first explanation that did not require me to already understand it.
Adding the clinical framing, because it changes how the question reads. Take it one variable at a time. Almost every unanswerable question in these threads is unanswerable because three things changed in the same fortnight, and no amount of subsequent argument can untangle them after the fact.
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View Resultsroxy_nash said:Almost every unanswerable question in these threads is unanswerable because three things changed in the same fortnight, and no amount of subsequent…
Mine went the same way, slower. Nothing to add that would improve it.
OP back with an update, since a thread like this is useless without one.
Update — my curve sits below the published mean and the explanation is that the trial arm had support I do not have. That was reassuring rather than otherwise.