Adding the clinical framing, because it changes how the question reads. The version of this that has an answer is narrower than the version being asked. Narrow it and it becomes tractable; leave it broad and the thread will produce nine confident and incompatible replies.
Adding the numbers, since they settle part of this. Keep the original post as written when you update it, and add the correction underneath. An edited-away mistake is invisible to the next person who makes it.
One thing that is still open after DoseLogDan’s answer:
What would you measure differently if you were starting again?
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View Resultshank_denver said:Keep the original post as written when you update it, and add the correction underneath.
I read this differently from hank_denver, on substance rather than tone. This treats a plausible mechanism as a demonstrated one. Plausible is where you start looking, not where you stop.
Ask again with the specifics and you will get a better answer than this one.