PeptideChemSF said:Receptor pharmacology relevant to the pharmacology: semaglutide is a GLP-1R agonist with a C-18 fatty acid chain that enables albumin binding (>99%),…
Agreed, and the size of the effect matters as much as its existence. Something real and small gets treated here as though it were real and decisive.
kate.chem said:The pharmacokinetics explain nearly every practical question asked here.
This answered a question I did not know how to ask. Sending this to two other people who asked me the same thing last week.
PeptideChemSF said:Receptor pharmacology relevant to the pharmacology: semaglutide is a GLP-1R agonist with a C-18 fatty acid chain that enables albumin binding (>99%),…
Pushing back on PeptideChemSF here. This treats a plausible mechanism as a demonstrated one. Plausible is where you start looking, not where you stop.
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View ResultsThe figures, for anyone assembling their own picture. Keep the original post as written when you update it, and add the correction underneath. An edited-away mistake is invisible to the next person who makes it.