NeuroNate said:Anxiety increase on mental health: counterintuitive, but losing weight rapidly triggered anxiety for me.
This is where I part company with the consensus forming above. I would be careful about how confidently the flatness reports get attributed. Rapid weight loss, a large deficit and disrupted sleep produce low mood on their own, and separating that from a drug effect is genuinely hard.
Happy to go further on any of that.
mel_PDX said:My mood has been flatter since about month four and I genuinely cannot work out whether that is the drug, the deficit, or the fact that I no longer…
Before/after narrative for mental health — one year in:
Before (282 lbs): Winded climbing stairs, chronic back pain, pre-diabetic, on 3 medications, dreaded mirrors, avoided photos, social anxiety about my weight.
After (187 lbs): Run 3 miles regularly, pain-free, A1C normal, down to 1 medication, bought a swimsuit for the first time in a decade, actually enjoy being photographed.
Total weight lost: 97 lbs. Total life gained: immeasurable. This isn't just about weight — it's about reclaiming your identity.
CarlaRPh_TPA said:I would be careful about how confidently the flatness reports get attributed.
When to call your doctor about mental health side effects — a reference I wish I'd had:
Call immediately:
- Severe abdominal pain (could be pancreatitis)
- Vision changes (thyroid concern)
- Lump in neck (thyroid nodule)
- Severe vomiting/can't keep fluids down for 24h+
Schedule an appointment:
- Persistent nausea beyond 4 weeks
- Significant hair loss
- Mood changes or depression
- Gallbladder symptoms (RUQ pain after eating)
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Browse GL BiochemA narrower follow-up, since the general answer is now clear:
How long did you give it before you decided it was working?
Closing the loop on my own question.
Follow-up — I put something in the gap where food used to be rather than waiting for the gap to close on its own. That was the part nobody told me.