gary_naperville said:HbA1c reflects roughly three months of average glycaemia weighted toward the most recent weeks, which is why repeating it at six weeks tells you very…
My labs after 9 months on glycaemic control: A1C 5.3%, fasting glucose 93 mg/dL, fasting insulin 4 uIU/mL. My endo says these are "textbook perfect."
For context, my baseline A1C was 8.1% and fasting glucose was 128 mg/dL. The improvement has been dramatic and consistent.
Following on from TinaHashiRN — and this may be the naive question:
Did your prescriber agree with that reading, and if not what was their objection?
NicoleRaleigh said:My labs after 9 months on glycaemic control: A1C 5.3%, fasting glucose 93 mg/dL, fasting insulin 4 uIU/mL.
PCOS success story with glycaemic control: as someone with polycystic ovary syndrome, this medication has been transformative beyond weight loss.
After 7 months: periods became regular for the first time in years, testosterone levels normalized, acne cleared significantly, and — unexpectedly — I got pregnant naturally after 4 years of trying.
GLP-1 agonists address the insulin resistance at the root of PCOS. For PCOS patients, this isn't "just" a weight loss drug — it's treating our underlying metabolic dysfunction.
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Browse GL BiochemNicoleRaleigh said:My labs after 9 months on glycaemic control: A1C 5.3%, fasting glucose 93 mg/dL, fasting insulin 4 uIU/mL.
Fasting insulin is the lab my functional medicine doctor cares about most for glycaemic control: it's a much earlier marker of metabolic dysfunction than glucose or A1C.
My fasting insulin: 28 → 14 → 7 uIU/mL over 9 months. Target is <7. By the time your fasting glucose is elevated, your insulin has been elevated for YEARS trying to compensate.
Ask your doctor to include fasting insulin in your bloodwork panel. It's cheap (~$20) and incredibly informative.
PedsEndoPhilly said:PCOS success story with glycaemic control: as someone with polycystic ovary syndrome, this medication has been transformative beyond weight loss.
Complete metabolic panel trending on glycaemic control — sharing because comprehensive data helps everyone:
| Test | Baseline | Month 3 | Month 6 | Month 12 |
|---|---|---|---|---|
| Glucose (fasting) | 128 | 106 | 88 | 84 |
| Insulin (fasting) | 24 | 14 | 8 | 7 |
| HOMA-IR | 4.5 | 3.9 | 1.6 | 1.2 |
| Uric Acid | 8.6 | 6.8 | 5.5 | 4.9 |
The insulin resistance improvement (HOMA-IR) is what my endo focuses on most. Going from 4.5 to near 1.0 is a metabolic transformation.