DataDave said:Reconstitution tip for anyone mixing dosing arithmetic from lyophilized powder: use bacteriostatic water, NOT sterile water.
Compounding pharmacy dose accuracy check for dosing arithmetic: I always verify my first dose from a new vial by weighing it on a milligram scale. Draw up your dose, weigh the syringe, subtract empty syringe weight, compare to expected water weight at that volume.
For a 10-unit dose (0.1mL): expected weight ~100mg of water. If it's significantly off, your syringe may be inaccurate. Cheap insulin syringes can have ±5% volume accuracy. Spring for quality brands like BD or Terumo.
DataDave said:Reconstitution tip for anyone mixing dosing arithmetic from lyophilized powder: use bacteriostatic water, NOT sterile water.
This is exactly what I could not find anywhere else. Printing the relevant bit and taking it with me.
From the other side of the consultation, briefly.
Comparison of compounded dosing arithmetic delivery formats I've tried:
| Format | Pros | Cons |
|---|---|---|
| Lyophilized vial | Longest shelf life, lowest cost | Requires reconstitution |
| Pre-mixed vial | Ready to draw up | Shorter shelf life (28-45 days) |
| Pre-filled syringes | Most convenient | Higher cost, shorter shelf life |
| Sublingual drops | No needles | Lower bioavailability, less data |
I use lyophilized vials for cost and stability. The reconstitution takes 30 seconds once you've done it a few times.
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Shop Reference StandardsPeptideChemSF said:Comparison of compounded dosing arithmetic delivery formats I've tried: Format Pros Cons Lyophilized vial Longest shelf life, lowest cost Requires…
Mine went the same way, slower. I had assumed I was the exception until I read this.
Reporting back.
The bulks-list asymmetry was the piece I had missed entirely. It explains why one of my two pharmacies is still arguing it can supply and the other simply stopped.