jim_asheville said:They are two different exemptions from the same federal requirements and they buy different things.
No disagreement with jim_asheville. One condition attached. Worth adding the genuine exception, because it is real and narrow: a change made for an identified patient where the prescriber determines it produces a significant clinical difference for that patient. A grid of fixed doses offered to everybody is not that, whatever the intake form says.
MounjBrad said:Agreed, and it is worth saying that rounding to the nearest whole unit is usually acceptable at maintenance doses and is not acceptable at the bottom…
This answered a question I did not know how to ask. I will report back once I have actually tried it.
jim_asheville said:They are two different exemptions from the same federal requirements and they buy different things.
Pushing back on jim_asheville here. A research-chemical supplier selling lyophilised powder labelled research use only is not compounding and is not claiming to. It is a different legal universe with no pharmacy oversight, no patient relationship and no content guarantee, and conflating the two in these threads helps nobody.
I would rather be corrected than agreed with, if it comes to it.
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Shop Reference StandardsFranDenver said:I reconstituted a 10mg vial with 2ml of bacteriostatic water and I want someone to check my unit arithmetic before I draw anything, because I keep…
Comparison of compounded dosing arithmetic delivery formats I've tried:
| Format | Pros | Cons |
|---|---|---|
| Lyophilized vial | Longest shelf life, lowest cost | Requires reconstitution |
| Pre-mixed vial | Ready to draw up | Shorter shelf life (28-45 days) |
| Pre-filled syringes | Most convenient | Higher cost, shorter shelf life |
| Sublingual drops | No needles | Lower bioavailability, less data |
I use lyophilized vials for cost and stability. The reconstitution takes 30 seconds once you've done it a few times.